Correct!
3. The chest radiograph and thoracic CT both show slight progression in the previously noted abnormalities

The chest radiograph shows relatively more right basal opacity with greater blunting of the right costophrenic angle, suggesting slight worsening in the previously noted abnormalities. The repeat thoracic CT appears fairly similar to the thoracic CT performed at presentation (Figure 2), perhaps with slight increase in size of the right paramediastinal process and associated consolidation. There is no evidence of left pleural liquid or new left-sided mediastinal lymph node enlargement, nor is there a new anterior mediastinal mass. The abnormalities noted on imaging at presentation have not shown any regression. No pericardial effusion is present.

Given the available data to this point, which of the following is the next most appropriate step for obtaining a diagnosis in this patient? (Click on the correct answer to proceed to the next panel)

  1. Percutaneous transthoracic fine needle aspiration and core biopsy
  2. Repeat bronchoscopy with endobronchial ultrasound and transbronchial biopsy
  3. Thoracoscopic surgical lung biopsy
  4. 1 or 3
  5. None of the above

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