Correct!
4. Glucocorticoids

Cryptogenic organizing pneumonia (COP) is one of the many causes of diffuse interstitial lung disease. Histologic findings of COP include extensive proliferation of granulation tissues affecting distal bronchioles and alveolar walls with patchy and peribronchiolar distribution (5). Patients with COP most commonly present with flu-like symptoms including cough, dyspnea, fever and general weakness, which are resistant to antibiotic treatment. There is no specific laboratory test for COP, and only 50 % of patients have leukocytosis. Glucocorticoids with careful attention to their adverse effect are recommended as an initial treatment for COP patients with persistent or worsening symptoms (6,7). Cytotoxic agents such as cyclophosphamide can be an alternative option for the patients who are refractory to steroid treatment.

High dose glucocorticoids were started. The patient’s respiratory status improved rapidly, and he was extubated successfully.

Which of the following disease is not included in steroid responsive interstitial lung disease?  (click on correct answer to move to next panel)

  1. Acute interstitial pneumonia (AIP)
  2. Desquamative interstitial pneumonia (DIP)
  3. Idiopathic pulmonary fibrosis (IPF)
  4. Nonspecific interstitial pneumonia (NSIP)
  5. Respiratory bronchiolitis interstitial lung disease (RBILD)

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