Correct!
5. Vancomycin, piperacillin/tazobactam, azithromycin, sulfamethoxazole/trimethoprim, fluconazole
This patient is at risk for hospital-acquired, resistant, opportunistic and endemic infections. Antimicrobials against methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas, atypical bacteria, pneumocystis and coccidioidomycosis are required in this case.
His bronchoalveolar lavage cytology revealed spherules consistent with Coccidioidomycosis immitis and treatment was changed to IV voriconazole, lipid amphotericin, piperacillin/tazobactam, and sulfamethoxazole/trimethoprim prophylaxis after cultures showed no MRSA.
The platelet count on admission was 264,000/ µL but five days later had decreased to 63,000/ µL. He had no other significant changes in laboratory values from admission. The patient was not on subcutaneous heparin prophylaxis given the concern for residual glioblastoma tumor and risk of intracerebral hemorrhage.
Which of the following is (are) a likely etiology (etiologies) for the thrombocytopenia? (click on correct answer to move to next panel)