Correct!
5. All of the above

There is no proven effective treatment for adenoviral hepatitis (4). Ribavirin and cidofovir have been utilized in anecdotal cases but require further study. Similarly, anecdotal reports of liver transplantation and reduction in immunosuppression have resulted in improvement.

Our patient was already receiving cidofovir and was not judged to be a candidate for liver transplantation or a reduction in immunosuppression. He was endotrancheally intubated on hospital day 3 with progressive liver, renal, and respiratory failure, and unfortunately, died on hospital day 5

References

1. Yen KT, Lee AS, Krowka MJ, Burger CD. Pulmonary complications in bone marrow transplantation: a practical approach to diagnosis and treatment. Clin Chest Med. 2004;25(1):189-201. [CrossRef]
2. Matthes-Martin S, Feuchtinger T, Shaw PJ, Engelhard D, Hirsch HH, Cordonnier C, Ljungman P. European guidelines for diagnosis and treatment of adenovirus infection in leukemia and stem cell transplantation: summary of ECIL-4 (2011). Transpl Infect Dis. 2012;14(6):555-63. [CrossRef] [PubMed]
3. McDonald GB, Shulman HM, Wolford JL, Spencer GD. Liver disease after human marrow transplantation. Semin Liver Dis. 1987;7(3):210-29. [CrossRef] [PubMed] 
4. Ronan BA, Agrwal N, Carey EJ, De Petris G, Kusne S, Seville MT, Blair JE, Vikram HR. Fulminant hepatitis due to human adenovirus. Fulminant hepatitis due to human adenovirus. Infection. 2013 Aug 24. [Epub ahead of print]. [CrossRef] [PubMed] 

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