Correct!
4.  Pulmonary alveolar proteinosis

The bronchoalveolar lavage fluid specimen shows abundant extracellular accumulation of proteinaceous periodic acid-Schiff (PAS)-positive material, consistent with pulmonary alveolar proteinosis.

Diagnosis:  Pulmonary alveolar proteinosis

Which of the following are therapies used to treat patients with pulmonary alveolar proteinosis?

1. Granulocyte-macrophage colony-stimulating factor
2. Whole lung lavage
3. Lung transplantation
4. B-lymphocyte depletion therapy with Rituximab
5. All of the above

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