Correct!
4. Granulomatosis with polyangiitis

Positive c-ANCA testing is not associated with the other diagnoses listed. The results of the renal biopsy- segmental necrotizing glomerulonephritis- are typical of granulomatosis with polyangiitis).

Diagnosis:  Granulomatosis with polyangiitis (aka ANCA-associated granulomatous vasculitis or Wegener’s Granulomatosis)

References

  1. Ananthakrishnan L, Sharma N, Kanne JP. Wegener's granulomatosis in the chest: high-resolution CT findings. AJR Am J Roentgenol. 2009; 192(3):676-682.
  2. Martinez F, Chung JH, Digumarthy SR, Kanne JP, Abbott GF, Shepard JO, Mark EJ, Sharma A. Common and uncommon manifestations of Wegener granulomatosis at chest CT: radiologic-pathologic correlation. Radiographics. 2012; 32(1):51-69.
  3. Falk RJ, Gross WL, Guillevin L, Hoffman GS, Jayne DR, Jennette JC, Kallenberg CG, Luqmani R, Mahr AD, Matteson EL, Merkel PA, Specks U, Watts RA, American College of Rheumatology, American Society of Nephrology, European League Against Rheumatism. Granulomatosis with polyangiitis (Wegener's): an alternative name for Wegener's granulomatosis. Arthritis Rheum. 2011; 63(4):863-864.
  4. Yi ES and Colby TV. Wegener’s granulomatosis. Semin Diagn Pathol. 2001; 18(1):34-46.

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