Correct!
4. 1 and 3

The patient had his antibiotics switched to linezolid and corticosteroids were begun for presumed daptomycin-induced lung disease. Although hookworm infection can present in immunocompromised hosts as a severe pneumonia, its rarity in the Southwest and the absence of parasites seen on smears make it unlikely. He rapidly improved and his corticosteroids were rapidly tapered because of his diabetes.

According to Kim et al. (4), daptomycin-induced eosinophilic lung disease can be diagnosed clinically (Table 2).

Table 2. Criteria for definite diagnosis of daptomycin-induced eosinophilic lung disease (4).

Based on these criteria, our patient would represent another case report of daptomycin-induced eosinophilic lung disease.

References

  1. Umpierrez G, Korytkowski M. Diabetic emergencies - ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia. Nat Rev Endocrinol. 2016 Apr;12(4):222-32. [CrossRef] [PubMed]
  2. Hansen LA, Prakash UB, Colby TV. Pulmonary complications in diabetes mellitus. Mayo Clin Proc. 1989 Jul;64(7):791-9. [CrossRef] [PubMed]
  3. Bhatt NY, Allen JN. Update on eosinophilic lung diseases. Semin Respir Crit Care Med. 2012;33(5):555-571. Available at: http://www.medscape.com/viewarticle/772354_14 (accessed 7/26/16). [CrossRef] [PubMed]
  4. Kim PW, Sorbello AF, Wassel RT, Pham TM, Tonning JM, Nambiar S. Eosinophilic pneumonia in patients treated with daptomycin: review of the literature and US FDA adverse event reporting system reports. Drug Saf. 2012 Jun 1;35(6):447-57. [CrossRef] [PubMed]

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