Correct!
1. Alveolar proteinosis

The clinical course, the radiologic pattern and the open lung biopsy are all compatible with alveolar proteinosis. Both the "crazy paving" pattern seen on the thoracic CT scan and the positive PAS material are nonspecific but in this clinical context are diagnostic of alveolar proteinosis.

Which of the following would be appropriate therapy in this case? (Click on the correct answer to proceed to the fourth of 5 panels)

1. Begin granulocyte macrophage-colony stimulating factor (GM-CSF)
2. Radiation to the whole lung
3. Whole lung lavage
4. 1 and 3
5. All of the above

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