Correct!
5. All of the above

Flow cytometry and careful examination of the peripheral smear revealed the presence of promyelocytes (Figure 2).

Figure 2. Peripheral smear showing two blasts.

The bone marrow aspiration biopsy resulted in a dry tap. However, the core biopsy showed hypercellular bone marrow compatible with acute promyelocytic leukemia (Figure 3).

Figure 3. High power view of the core bone marrow biopsy showing hypercellularity with multiple promyelocytes.

FISH for the chromosomal translocation involving the retinoic acid receptor alpha (RARα or RARA) gene on chromosome 17 on the peripheral blood was positive.

Which of the following are true regarding acute promyelocytic leukemia (APL)? (Click on the correct answer to proceed to the fifth and last panel)

1. APL can be a manifestation of arsenic poisoning
2. APL is a common leukemia
3. APL is a medical emergency and treatment should be initiated with all-trans retinoic acid
4. 1 and 3
5. All of the above

Home/Critical Care