Correct!
5. All of the above

Diffuse alveolar hemorrhage (DAH) is most often recognized by obtaining a bloody return when bronchial alveolar lavage (BAL) is performed. The differential for diffuse bronchial alveolar hemorrhage is vast and requires a series of investigations for a definite etiology. We can classify DAH as a clinical picture which consists of anemia, hemoptysis, and respiratory failure (hypoxic in origin) and diffuse radiographic pulmonary infiltration.

In our patient the lab findings were consistent with diagnosis of necrotizing granulomatous vasculitis (NGV, formerly known as Wegner’s granulomatous disease). He did not have any history suggesting exposure to cytotoxic drugs and there were no risk factors in him which would make us concerned for sub-acute bacterial endocarditis.

Therapy most appropriate for a patient with NGV may include: (Click on the correct answer to move to the last panel)

  1. Cyclophosphamide
  2. High dose steroids
  3. Plasma exchange
  4. Rituximab
  5. All of the above

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